Intraoperative 68Ga-PSMA Cerenkov Luminescence Imaging for Surgical Margins in Radical Prostatectomy: A Feasibility Study
نویسندگان
چکیده
منابع مشابه
Intraoperative imaging of tumors using Cerenkov luminescence endoscopy: a feasibility experimental study.
UNLABELLED Cerenkov luminescence imaging (CLI) is an emerging new molecular imaging modality that is relatively inexpensive, easy to use, and has high throughput. CLI can image clinically available PET and SPECT probes using optical instrumentation. Cerenkov luminescence endoscopy (CLE) is one of the most intriguing applications that promise potential clinical translation. We developed a protot...
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In early-stage breast cancer, the primary treatment option for most women is breast-conserving surgery (BCS). There is a clear need for more accurate techniques to assess resection margins intraoperatively, because on average 20% of patients require further surgery to achieve clear margins. Cerenkov luminescence imaging (CLI) combines optical and molecular imaging by detecting light emitted by ...
متن کاملReporting positive surgical margins after radical prostatectomy: time for standardization.
OBJECTIVES To assess the consistency of reporting on positive surgical margins (PSMs) and associated prognostic variables after radical prostatectomy (RP) in the current literature To provide a standardized methodology for quantifying the characteristics and the prognostic impact of PSMs after RP. PATIENTS AND METHODS We conducted a review of articles that assessed the prognostic value of cha...
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We retrospectively assessed 117 consecutive hormone-naïve BCR patients who had Ga-PSMA 11 PET/CT (n = 46) or PET/MRI (n = 71) between May 2014 and January 2017. BCR was defined as two PSA rises above 0.2 ng/ml. Two dedicated uro-oncological imaging experts (radiology/nuclear medicine) reviewed separately all images. All results were presented in a blinded sequential fashion to a multidisciplina...
متن کامل[Positive surgical margins after radical prostatectomy]. - PubMed - NCBI
Abstract Positive surgical margins (PSMs) in radical prostatectomy specimens are usually considered a negative prognostic parameter. However, their definition and the management of patients with PSMs remain unclear. The aim of the present review is to define pathological features of PSMs,to report their incidence and risk factors and to update PSMs prognostic meaning and possible treatment moda...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2020
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.119.240424